| 103* | J Logtenberg | v Pakistan Women at Pretoria, 4th ODI, 2006/07 [591] |
| 101* | L Olivier | v Ireland Women at Christchurch, CricInfo Women's World Cup, 2000/01 [359] |
| 91* | KA Laing | v India Women at Johannesburg, 1st ODI, 2001/02 [399] |
| 81 | M Terblanche | v England Women at Pretoria, 3rd ODI, 2003/04 [466] |
| 79* | J Logtenberg | v Pakistan Women at Pretoria, 1st ODI, 2006/07 [588] |
| 79 | M Terblanche | v England Women at Bristol, 2nd ODI, 2003 [453] |
| 78* | L Olivier | v Ireland Women at Pune, Hero Honda Women's World Cup, 1997/98 [253] |
| 76 | J Logtenberg | v England Women at Potchefsroom, 5th ODI, 2003/04 [472] |
| 74* | A Kuylaars | v Pakistan Women at Baroda, Hero Honda Women's World Cup, 1997/98 [258] |
| 72 | C Brits | v West Indies Women at Pretoria, Women's World Cup, 2004/05 [515] |
| 68 | M Terblanche | v West Indies Women at Pretoria, 1st ODI, 2004/05 [533] |
| 67 | KA Laing | v England Women at Worcester, 5th ODI, 2000 [324] |
| 67 | J Logtenberg | v England Women at Port Elizabeth, 1st ODI, 2003/04 [462] |
| 64 | HA Davies | v England Women at Bristol, 1st ODI, 1997 [232] |
| 62* | C Brits | v West Indies Women at Pretoria, 3rd ODI, 2004/05 [536] |
| 62 | CE Eksteen | v England Women at Taunton, 4th ODI, 2000 [323] |
| 61 | J Logtenberg | v England Women at Bristol, 2nd ODI, 2003 [453] |
| 61 | CS Terblanche | v Pakistan Women at Pretoria, 5th ODI, 2006/07 [592] |
| 60 | L Olivier | v England Women at Taunton, 2nd ODI, 1997 [233] |
| 58 | SM Benade | v Pakistan Women at Pretoria, 4th ODI, 2006/07 [591] |
| 57* | A Kuylaars | v England Women at Taunton, 4th ODI, 2000 [323] |
| 57 | L Olivier | v England Women at Lord's, 3rd ODI, 1997 [234] |
| 57 | C Brits | v Pakistan Women at Pretoria, 3rd ODI, 2006/07 [590] |
| 56* | KA Laing | v Ireland Women at Belfast, 1st ODI, 1997 [229] |
| 56* | L Olivier | v Ireland Women at Dublin, 3rd ODI, 1997 [231] |
| 56 | DJ Reid | v England Women at Taunton, 2nd ODI, 1997 [233] |
| 55* | M du Preez | v Pakistan Women at Pretoria, 5th ODI, 2006/07 [592] |
| 55 | J Logtenberg | v England Women at Potchefstroom, 2nd ODI, 2004/05 [507] |
| 54* | S Viljoen | v England Women at Lincoln, CricInfo Women's World Cup, 2000/01 [337] |
| 54 | C Brits | v Pakistan Women at Pretoria, 2nd ODI, 2006/07 [589] |
| 53* | M Terblanche | v Sri Lanka Women at Lincoln, CricInfo Women's World Cup, 2000/01 [347] |
| 53 | C Brits | v West Indies Women at Pretoria, 1st ODI, 2004/05 [533] |
| 52* | AA Burger | v Ireland Women at Dublin, 3rd ODI, 1997 [231] |
| 52* | AL Hodgkinson | v England Women at Cardiff, 3rd ODI, 2003 [454] |
| 52 | L Olivier | v England Women at Chelmsford, 1st ODI, 2000 [320] |
| 51 | L Olivier | v Australia Women at Bangalore, Hero Honda Women's World Cup, 1997/98 [246] |
| 51 | L Olivier | v Denmark Women at Baroda, Hero Honda Women's World Cup, 1997/98 [262] |
| 51 | M Terblanche | v England Women at Chelmsford, 1st ODI, 2003 [452] |
